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Di laman Manosa:
"Protein rekombinan yang dihasilkan dalam yis mungkin tertakluk kepada penambahan manosa dalam corak yang berbeza daripada yang digunakan oleh sel mamalia.[1] Perbezaan dalam protein rekombinan ini daripada yang biasanya dihasilkan dalam organisma mamalia mungkin mempengaruhi keberkesanan vaksin.[perlu rujukan]
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