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In page Marianne Frommer:
"Frommer then determined the chromosomal locations of the major simple-sequence repeats by devising a new method of non-radioactive labelling, based on incorporation of bromodeoxyuridine into single-stranded probes.[3] The method was used to localise satellite repeats very precisely. This research led to the observation of methylation patterns at CpG dinucleotides in sequenced genomic repeated DNA.[citation needed]
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