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In page Amita Sehgal:
"Mushroom bodies are located in the brains of Drosophila and are known to play a role in learning, memory, olfaction, and locomotion.[1] In 2006, Sehgal and her colleagues discovered that mushroom bodies also play a major role in regulating sleep in flies. By using a steroid called RU-486 (Mifepristone) to regulate protein kinase A (PKA), they were able to upregulate and downregulate the expression of genes in specific areas like the mushroom bodies, and found that this structure is critical for fly sleep.[2] While the specific pathway through which these mushroom bodies regulate sleep is currently unknown, it may be that they are involved in inhibiting processing of sensory information, allowing flies to fall asleep.[citation needed]
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