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In page Simultaneously extracted metals and acid-volatile sulfide:

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In order for toxic substances like heavy metals to cause effects in organisms, they must be bioavailable.[1] For organisms residing in contaminated sediments, the contaminants are most bioavailable when dissolved in the pore water, as opposed to being precipitated as a solid or sorbed to a sediment particle.[2] Metals in the solid metal-sulfide form are thus considered non-bioavailable, and are unlikely to cause toxicity in sediment-dwelling organisms.[citation needed]