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In page Cause (medicine):

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Etiological discovery in medicine has a history in Robert Koch's demonstration that species of the pathogenic bacteria Mycobacterium tuberculosis causes the disease tuberculosis; Bacillus anthracis causes anthrax, and Vibrio cholerae causes cholera. This line of thinking and evidence is summarized in Koch's postulates. But proof of causation in infectious diseases is limited to individual cases that provide experimental evidence of etiology.[citation needed]