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In page Congenital myasthenic syndrome:
"Postsynaptic fast-channel CMS, in which ACh receptors do not stay open long enough, is treated with cholinesterase inhibitors and 3,4-diaminopyridine.[1][2] In the U.S., the more stable phosphate salt formulation of 3,4-diaminopyridine (amifampridine phosphate) is under development as an orphan drug for CMS and is available to eligible patients at no cost under an expanded access program.[3][4] Postsynaptic slow-channel CMS is treated with quinidine or fluoxetine, which blocks the ACh receptor.[citation needed]
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