Citation Hunt

Leaderboard

The Wikipedia snippet below is not backed by a reliable source. Can you find one?

Click I got this! to go to Wikipedia and fix the snippet, or Next! to see another one. Good luck!

In page Cell-free fetal DNA:

"

Differences in gene activation between maternal and fetal DNA can be exploited. Epigenetic modifications (heritable modifications that change gene function without changing DNA sequence) can be used to detect cffDNA.[1][2] The hypermethylated RASSF1A promoter is a universal fetal marker used to confirm the presence of cffDNA.[3] A technique was described where cffDNA was extracted from maternal plasma and then digested with methylation-sensitive and insensitive restriction enzymes. Then, real-time PCR analysis of RASSF1A, SRY, and DYS14 was done.[3] The procedure detected 79 out of 90 (88 percent) maternal blood samples where hypermethylated RASSF1A was present.[citation needed]