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In page Centor criteria:

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The presence of all four variables indicates a 40–60% positive predictive value for a culture of the throat to test positive for Group A streptococcus bacteria. The absence of all four variables indicates a negative predictive value of greater than 80%.[2] The high negative predictive value suggests that the Centor criteria can be more effectively used for ruling out strep throat than for diagnosing strep throat.[citation needed]