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In page Conorenal syndrome:

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When originally characterized by Giedion, there was a relatively high mortality rate due to untreated kidney failure (end stage kidney disease - ESKD). The remarkable improvements in kidney transplantation have reduced the mortality of Conorenal Syndrome substantially if not eliminated it entirely. Most diagnosis of the disease occurs when children present with kidney failure – usually between the ages of 10 and 14. There is no known cure for the syndrome and management of the syndrome is supportive.[citation needed]