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In page Asemia:

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The most common cause of asemia is brain damage, such as a stroke or a brain tumor.[1] Other possible causes include Alzheimer's disease and infection.[1] Roger Wolcott Sperry, through his research of split-brain patients, had found out that the human brain lateralizes functions, meaning that the two hemispheres of the brain have different functions.[2] Brain damage, specifically to the left hemisphere, can impair our ability to speak or understand language.[3] This led Sperry to conclude that due to the lateralization of brain function, language is based in the left hemisphere.[2] Therefore, any kind of brain damage to the left hemisphere will greatly impact language, whether it is expressive or receptive.[citation needed]