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In page Complex regional pain syndrome:

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The mechanisms leading to reduced bone mineral density (up to overt osteoporosis) are still unknown. Potential explanations include a dysbalance of the activities of sympathetic and parasympathetic autonomic nervous system[15][16][17] and mild secondary hyperparathyroidism.[18][19][20] However, the trigger of secondary hyperparathyroidism has not yet been identified.[citation needed]