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In page Heterochromia:
"
- Certain eyedrops – prostaglandin analogues (latanoprost, isopropyl unoprostone, travoprost, and bimatoprost) are used topically to lower intraocular pressure in glaucoma patients. A concentric heterochromia has developed in some patients applying these drugs. A stimulation of melanin synthesis within iris melanocytes has been postulated.[1]
- Neoplasm – Nevi and melanomatous tumors.[citation needed]
- Iridocorneal endothelium syndrome[2]
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