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In page Chest drainage:

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In a two-chamber system air and fluid are directed to a first collection canister. Gravity keeps the fluid in the first canister, whereas air is directed into a second canister. The air can either actively or passively be released via a water seal. Two-chamber systems are mainly used for patients with huge air leaks. These patients often produce foam due to protein rich surfactant that might enter the tubing toward the patient.[citation needed]