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"The CPT system directly acts on the transfer of fatty acids between the cytosol and the inner mitochondrial matrix.[1] CPT II shares structural elements with other members of the carnitine acyltransferase protein family.[2] The crystal structure of rat CPT II was in 2006 elucidated by Hsiao et al.[3] The human homolog of the CPT II enzyme shows 82.2% amino acid sequence homology with the rat protein.[4] Significant structural and functional information about CPT II has thus been derived from the crystallographic studies with the rat protein.[citation needed]
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