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In page Autoimmune retinopathy:

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A key feature of the adaptive immune system is the development of immune system memory, which can lead to autoimmune diseases being chronic. In AIR, once the immune system has been exposed to retinal antigens, it continues to produce autoreactive antibodies and T cells even in the absence of an initial trigger. This chronic immune response is a primary factor in the long-term and progressive retinal damage observed in AIR.[citation needed]