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In page Atheroma:

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The accumulation (swelling) is always in the tunica intima, between the endothelium lining and the smooth muscle middle layer of the artery wall.[citation needed]While the early stages, based on gross appearance, have traditionally been termed fatty streaks by pathologists, they are not composed of fat cells but of accumulations of foam cells, which are macrophages that have taken up oxidized low-density lipoprotein (LDL).[1]