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In page Heyde's syndrome:

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In the 45 years following its initial description, no plausible explanations could be found for the association between aortic valve stenosis and gastrointestinal bleeding. Indeed, the association itself was questioned by a number of researchers.[2][3] Several studies demonstrated a statistically significant association between aortic stenosis and gastrointestinal bleeding,[4][5][6] and in 1987 King et al. even noted the successful resolution of bleeding symptoms with aortic valve replacement in 93% of people, compared to just 5% in people where the bleeding was treated surgically.[7] However, the potential causal association between the two conditions remained elusive and controversial.[citation needed]