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In page Cardiac output:
"The UD method is based on ultrasound indicator dilution.[7] Blood ultrasound velocity (1560–1585 m/s) is a function of total blood protein concentration—sums of proteins in plasma and in red blood red cells—and temperature. Injection of body-temperature normal saline (ultrasound velocity of saline is 1533 m/s) into a unique AV loop decreases blood ultrasound velocity, and produces dilution curves.[citation needed]
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