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In page Autologous conditioned serum:
"Autologous conditioned serum is a patented method developed by molecular biologist Julio Reinecke and Peter Wehling, a spinal surgeon in Düsseldorf, Germany.[1][2] Orthokine was first approved for use in Germany in 2003.[3] Orthokine differs from a similar procedure with platelet-rich plasma (PRP),[4] where platelets are targeted instead of the interleukin antagonist. Also, PRP does not require the blood to be heated as Orthokine does.[citation needed]
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