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In page Autoimmune retinopathy:
"The innate immune response in AIR is often triggered when immune cells recognize damage-associated molecular patterns (DAMPs) released by damaged retinal cells. These signals are detected by pattern recognition receptors (PRRs) on innate immune cells such as macrophages and dendritic cells. Once activated, these cells release pro-inflammatory cytokines, which can further promote inflammation within the retina. While these inflammatory mediators can normally help to fight infections, in autoimmune diseases like AIR, they progress tissue damage by promoting the activation of both the innate and adaptive immune responses within the body.[citation needed]
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