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In page Juana Briones de Miranda:

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After establishing a farm at El Polín Spring near the Presidio of San Francisco, she bought land and built a house at Yerba Buena, the area of San Francisco today known as North Beach. A natural entrepreneur, she marketed her milk and produce to the sailors from whaling ships or those who arrived in port for the hide and tallow trade. Briones excelled not only in business and farming: her reputation for hospitality and skills in herbal medicine and midwifery were widely recognized. She trained her nephew, Pablo Briones – who was later known as the Doctor of Bolinas (California) – in medicinal arts, although she never received a formal education and could not read or write.[citation needed]