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In page Emil Kraepelin:

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Kraepelin postulated that there is a specific brain or other biological pathology underlying each of the major psychiatric disorders.[1] As a colleague of Alois Alzheimer, he was a co-discoverer of Alzheimer's disease, and his laboratory discovered its pathological basis. Kraepelin was confident that it would someday be possible to identify the pathological basis of each of the major psychiatric disorders.[citation needed]