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In page Blood–brain barrier:
"The blood–brain barrier may become damaged in certain neurological diseases, as indicated by neuroimaging studies of Alzheimer's disease, amyotrophic lateral sclerosis, epilepsy, hemorrhagic stroke,[1] ischemic stroke,[2][3][4][5] and brain trauma,[6] and in systemic diseases, such as liver failure.[7] However, in many neurodegenerative diseases, the exact cause and pathology remains unknown.[citation needed]
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