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In page Edward Gibbon:

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Among Edward Gibbon's maladies was gout.[2] Gibbon is also believed to have suffered from an extreme case of scrotal swelling, probably a hydrocele testis, a condition that causes the scrotum to swell with fluid in a compartment overlying either testicle.[3] In an age when close-fitting clothes were fashionable, his condition led to a chronic and disfiguring inflammation that left Gibbon a lonely figure.[4] As his condition worsened, he underwent numerous procedures to alleviate the condition, but with no enduring success. In early January, the last of a series of three operations caused an unremitting peritonitis to set in and spread, from which he died.[citation needed]