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In page Transcription factor:
"Transcription factors may be activated (or deactivated) through their signal-sensing domain by a number of mechanisms including:
- phosphorylation[1][2] – Many transcription factors such as STAT proteins must be phosphorylated before they can bind DNA.
- interaction with other transcription factors (e.g., homo- or hetero-dimerization) or coregulatory proteins[citation needed]
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