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In page G protein-coupled receptor:

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GPCRs are involved in a wide variety of physiological processes. Some examples of their physiological roles include:

  1. The gustatory sense (taste): GPCRs in taste cells mediate release of gustducin in response to bitter-, umami- and sweet-tasting substances.[citation needed]
  2. The sense of smell: Receptors of the olfactory epithelium bind odorants (olfactory receptors) and pheromones (vomeronasal receptors)[citation needed]
  3. Behavioral and mood regulation: G protein-coupled receptors in the mammalian brain bind several different neurotransmitters, including serotonin, dopamine, histamine, noradrenaline, and GABA. Notable exceptions include GABAA receptor,[1] 5-HT3 serotonin receptor[2] and glutamate receptors (NMDAR, AMPAR and kainate receptor),[3] which are ion channels.