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In page Myelodysplastic syndrome:

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Dysplasia can affect all three lineages seen in the bone marrow. The best way to diagnose dysplasia is by morphology and special stains (PAS) used on the bone marrow aspirate and peripheral blood smear. Dysplasia in the myeloid series is defined by:

  • Granulocytic series[citation needed]:
    1. Hypersegmented neutrophils (also seen in vit B12/folate deficiency)
    2. Hyposegmented neutrophils (pseudo Pelger-Huet)
    3. Hypogranular neutrophils or pseudo Chediak-Higashi (large azurophilic granules)
    4. Auer rods – automatically RAEB II (if blast count < 5% in the peripheral blood and < 10% in the bone marrow aspirate); also note Auer rods may be seen in mature neutrophils in AML with translocation t(8;21)
    5. Dimorphic granules (basophilic and eosinophilic granules) within eosinophils