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In page Hyperthyroidism:

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The major causes in humans are:

  • Graves' disease. An autoimmune disease (usually, the most common cause with 50–80% worldwide, although this varies substantially with location- i.e., 47% in Switzerland (Horst et al., 1987) to 90% in the USA (Hamburger et al. 1981)). Thought to be due to varying levels of iodine in the diet.[3] It is eight times more common in females than males and often occurs in young females, around 20 to 40 years of age.[citation needed]
  • Toxic thyroid adenoma (the most common cause in Switzerland, 53%, thought to be atypical due to a low level of dietary iodine in this country)[3]