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In page Neurotransmitter:
"In addition, over 100 neuroactive peptides have been found, and new ones are discovered regularly.[4][5] Many of these are co-released along with a small-molecule transmitter. Nevertheless, in some cases, a peptide is the primary transmitter at a synapse. Beta-Endorphin is a relatively well-known example of a peptide neurotransmitter because it engages in highly specific interactions with opioid receptors in the central nervous system.[citation needed]
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