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In page Headache:
"Preventive medications are generally recommended when people have more than four attacks of migraine per month, headaches last longer than 12 hours or the headaches are very disabling.[1][2] Possible therapies include beta blockers, antidepressants, anticonvulsants and NSAIDs.[2] The type of preventive medicine is usually chosen based on the other symptoms the person has. For example, if the person also has depression, an antidepressant is a good choice.[citation needed]
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