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In page Aconitum:

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Aconitine is a potent neurotoxin and cardiotoxin that causes persistent depolarization of neuronal sodium channels in tetrodotoxin-sensitive tissues.[citation needed] The influx of sodium through these channels and the delay in their repolarization increases their excitability and may lead to diarrhea, convulsions, ventricular arrhythmia, and death.[citation needed]