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In page W. Edwards Deming:

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Deming's collaboration with Hans Lineweaver and Dean Burk[1] is possibly the least known of his work as a statistician, but it is relevant to what has become the most highly cited paper[2] ever published in the Journal of the American Chemical Society,[3] which was written after the authors had consulted Deming about the proper way to analyze their data. Although they are credited with the introduction of the double-reciprocal plot, in which the reciprocal rate is plotted against the reciprocal substrate concentration, they estimated the kinetic parameters by weighted linear regression with weights of the fourth power of the rates, as recommended by Deming. Unfortunately this (essential) part of their approach was quickly forgotten.[citation needed]