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In page Antacid:

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When an excess amount of acid is produced in the stomach, the natural mucous barrier that protects the lining of the stomach can degrade, leading to pain and irritation.[1] There is also potential for the development of acid reflux, which can cause pain and damage to the esophagus.[citation needed] Antacids contain alkaline ions that chemically neutralize stomach gastric acid, reducing damage to the stomach lining and esophagus, and relieving pain.[2] Some antacids also inhibit pepsin, an enzyme that can damage the esophagus in acid reflux.[3][4]

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