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In page Phocomelia:
"A study of Roberts syndrome, a genetic disorder showing similar symptoms to phocomelia, has shed light on the possible causes.[2] An individual afflicted with Roberts Syndrome will have chromosome copies that do not connect at the centromeres, making them unable to line up accordingly.[3] As a result, the newly made cells contain an excess or reduced number of chromosomes. In both Roberts syndrome and phocomelia the cells cease to develop, or die, preventing proper development of the limbs, eyes, brain, palate, or other structures.[citation needed]
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