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In page Superoxide dismutase:

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SOD has been used in experimental treatment of chronic inflammation in inflammatory bowel conditions.[1][2] SOD may ameliorate cis-platinum-induced nephrotoxicity (rodent studies).[3] As "Orgotein" or "ontosein", a pharmacologically-active purified bovine liver SOD, it is also effective in the treatment of urinary tract inflammatory disease in man.[4] For a time, bovine liver SOD even had regulatory approval in several European countries for such use. This was cut short by concerns about prion disease.[citation needed]