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The entire procedure is very quick, typically taking about five minutes. The success rate of these procedures is high[4] and is very promising for future treatment in humans. One disadvantage to using N-TIRE is that the electricity delivered from the electrodes can stimulate muscle cells to contract, which could have lethal consequences depending on the situation. Therefore, a paralytic agent must be used when performing the procedure. The paralytic agents that have been used in such research are successful[citation needed]; however, there is always some risk, albeit slight, when using anesthetics.