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In page Phenylketonuria:

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The average number of new cases of PKU varies in different human populations. United States Caucasians are affected at a rate of 1 in 10,000.[7] Turkey has the highest documented rate in the world, with 1 in 2,600 births, while countries such as Finland and Japan have extremely low rates with fewer than one case of PKU in 100,000 births. A 1987 study from Slovakia reports a Roma population with an extremely high incidence of PKU (one case in 40 births) due to extensive inbreeding.[8] It is the most common amino acid metabolic problem in the United Kingdom.[citation needed]