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In page Ivan Pavlov:

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The fellowship and his position as director of the Physiological Laboratory at Botkin's clinic enabled Pavlov to continue his research work.[citation needed] In 1883, he presented his doctor's thesis on the subject of The centrifugal nerves of the heart and posited the idea of nerves and the basic principles on the trophic function of the nervous system. Additionally, his collaboration with the Botkin Clinic produced evidence of a basic pattern in the regulation of reflexes in the activity of circulatory organs.[citation needed]