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In page Hypothetical types of biochemistry:

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It is questionable, however, whether such a biochemistry would be truly alien. Although it would certainly be an alternative stereochemistry, molecules that are overwhelmingly found in one enantiomer throughout the vast majority of organisms can nonetheless often be found in another enantiomer in different (often basal) organisms such as in comparisons between members of Archaea and other domains,[citation needed] making it an open topic whether an alternative stereochemistry is truly novel.