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In page Gene knockout:
"Zinc-finger nucleases consist of DNA binding domains that can precisely target a DNA sequence.[1] Each zinc-finger can recognize codons of a desired DNA sequence, and therefore can be modularly assembled to bind to a particular sequence.[2] These binding domains are coupled with a restriction endonuclease that can cause a double stranded break (DSB) in the DNA.[1] Repair processes may introduce mutations that destroy functionality of the gene.[citation needed]
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