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In page Transdifferentiation:

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  • Transdifferentiation can also be much more efficient than pluripotency reprogramming due to the extra step involved in the latter process.[2]
  • Both pluripotent and transdifferentiated cells use adult cells, thus starting cells are very accessible, whereas human embryonic stem cells require that one navigate legal loopholes and delve into the morality of stem cell research debate.[citation needed]