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In page Cell theory:

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Harvey and Danielli (1939) proposed a lipid bilayer membrane covered on each side with a layer of protein to account for measurements of surface tension. In 1941 Boyle and Conway showed that the membrane of frog muscle was permeable to both K+ and Cl, but apparently not to Na+, so the idea of electrical charges in the pores was unnecessary since a single critical pore size would explain the permeability to K+, H+, and Cl as well as the impermeability to Na+, Ca+, and Mg2+. Over the same time period, it was shown (Procter and Wilson, 1916) that gels, which do not have a semipermeable membrane, would swell in dilute solutions.[citation needed]