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In page Ryōji Noyori:
"Noyori is most famous for asymmetric hydrogenation using as catalysts complexes of rhodium and ruthenium, particularly those based on the BINAP ligand. Asymmetric hydrogenation of an alkene in the presence of ((S)-BINAP)Ru(OAc)2 is used for the commercial production of enantiomerically pure (97% ee) naproxen, a nonsteriodal anti-inflammatory drug. The antibacterial agent levofloxacin is manufactured by asymmetric hydrogenation of ketones in the presence of a Ru(II) BINAP halide complex.[citation needed]
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