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In page Muhammad:

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The pre-Islamic Middle East was dominated by the Byzantine and Sasanian empires. The Roman–Persian Wars between the two had devastated the region, making the empires unpopular amongst local tribes. Furthermore, in the lands that would be conquered by Muslims, many Christians (Nestorians, Monophysites, Jacobites and Copts) were disaffected from the Eastern Orthodox Church which deemed them heretics. Within a decade Muslims conquered Mesopotamia, Byzantine Syria, Byzantine Egypt,[4] large parts of Persia, and established the Rashidun Caliphate.[citation needed]